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2021 年 1 月安捷伦细胞分析出版物快报

人阅读 发布时间:2021-01-27 10:31

每个月的出版物快报都会展示包含Seahorse XF和可溶性代谢探针数据的同行评审文献。 请查看您研究领域中的新文献,了解有关其他科研人员如何在其研究中使用安捷伦细胞分析产品的更多信息。


Aging Research  

Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors

Cancer Research

Increased glutathione utilization augments tumor cell proliferation in Waldenstrom Macroglobulinemia
Jalali, S., Shi, J., Buko, A., Ahsan, N., Paludo, J., Serres, M., Wellik, L. E., Abeykoon, J., Kim, H., Tang, X., Yang, Z. Z., Novak, A. J., Witzig, T. E. and Ansell, S. M.
Redox Biol. 2020 Sep, 36:101657.

Cancer‐induced cardiac atrophy adversely affects myocardial redox state and mitochondrial oxidative characteristics
Lee, D. E., Brown, J. L., Rosa‐Caldwell, M. E., Perry, R. A., Brown, L. A., Haynie, W. S., Washington, T. A., Wiggs, M. P., Rajaram, N. and Greene, N. P.
JCSM Rapid Communications. 2020 Aug 7, [epub ahead of print]

The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation
Kosti, A., de Araujo, P. R., Li, W. Q., Guardia, G. D. A., Chiou, J., Yi, C., Ray, D., Meliso, F., Li, Y. M., Delambre, T., Qiao, M., Burns, S. S., Lorbeer, F. K., Georgi, F., Flosbach, M., Klinnert, S., Jenseit, A., Lei, X., Sandoval, C. R., Ha, K., Zheng, H., Pandey, R., Gruslova, A., Gupta, Y. K., Brenner, A., Kokovay, E., Hughes, T. R., Morris, Q. D., Galante, P. A. F., Tiziani, S. and Penalva, L. O. F.
Genome Biol. 2020 Aug 6, 21(1):195.

Kinetic Heterogeneity of Cancer Cell Fractional Killing
Inde, Z., Forcina, G. C., Denton, K. and Dixon, S. J.
Cell Rep. 2020 Jul 7, 32(1):107845.

Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells
Kawashima, M., Bensaad, K., Zois, C. E., Barberis, A., Bridges, E., Wigfield, S., Lagerholm, C., Dmitriev, R. I., Tokiwa, M., Toi, M., Papkovsky, D. B., Buffa, F. M. and Harris, A. L.
Cancer Metab. 2020 Jul 6, 8:13.

Mitochondrial TXNRD3 confers drug resistance via redox-mediated mechanism and is a potential therapeutic target in vivo
Liu, X., Zhang, Y., Lu, W., Han, Y., Yang, J., Jiang, W., You, X., Luo, Y., Wen, S., Hu, Y. and Huang, P.
Redox Biol. 2020 Sep, 36:101652.

Methiothepin Suppresses Human Ovarian Cancer Cell Growth by Repressing Mitochondrion-Mediated Metabolism and Inhibiting Angiogenesis In Vivo
Lee, J. Y., Yang, C., Lim, W. and Song, G.
Pharmaceutics. 2020 Jul 20, 12(7):686.

Mitochondrial ubiquinol oxidation is necessary for tumour growth
Martinez-Reyes, I., Cardona, L. R., Kong, H., Vasan, K., McElroy, G. S., Werner, M., Kihshen, H., Reczek, C. R., Weinberg, S. E., Gao, P., Steinert, E. M., Piseaux, R., Budinger, G. R. S. and Chandel, N. S.
Nature. 2020 Sep, 585(7824):288-292.

The c-Rel-c-Myc axis controls metabolism and proliferation of human T leukemia cells
Li, X., Luo, G., Li, T., Sun, H., Wang, W., Eiler, E., Goldsmith, J. R. and Chen, Y. H.
Mol Immunol. 2020 Sep, 125:115-122.

CircPOSTN/miR-361-5p/TPX2 axis regulates cell growth, apoptosis and aerobic glycolysis in glioma cells
Long, N., Chu, L., Jia, J., Peng, S., Gao, Y., Yang, H., Yang, Y., Zhao, Y. and Liu, J.
Cancer Cell Int. 2020 Aug 6, 20:374.

Predictive biomarkers for 5-ALA-PDT can lead to personalized treatments and overcome tumor-specific resistances
Mastrangelopoulou, M., Grigalavicius, M., Raabe, T. H., Skarpen, E., Juzenas, P., Peng, Q., Berg, K. and Theodossiou, T. A.
Cancer Rep (Hoboken). 2020 Jul 31, e1278.

Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis
Nassar, Z. D., Mah, C. Y., Dehairs, J., Burvenich, I. J., Irani, S., Centenera, M. M., Helm, M., Shrestha, R. K., Moldovan, M., Don, A. S., Holst, J., Scott, A. M., Horvath, L. G., Lynn, D. J., Selth, L. A., Hoy, A. J., Swinnen, J. V. and Butler, L. M.
Elife. 2020 Jul 20, 9:e54166.

Ascorbate sensitizes human osteosarcoma cells to the cytostatic effects of cisplatin
Oka, N., Komuro, A., Amano, H., Dash, S., Honda, M., Ota, K., Nishimura, S., Ueda, T., Akagi, M. and Okada, H.
Pharmacology Research & Perspectives. 2020 Aug, 8(4): e00632.

Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
Schiffmann, L. M., Werthenbach, J. P., Heintges-Kleinhofer, F., Seeger, J. M., Fritsch, M., Gunther, S. D., Willenborg, S., Brodesser, S., Lucas, C., Jungst, C., Albert, M. C., Schorn, F., Witt, A., Moraes, C. T., Bruns, C. J., Pasparakis, M., Kronke, M., Eming, S. A., Coutelle, O. and Kashkar, H.
Nat Commun. 2020 Jul 21, 11(1):3653.

Coordinate beta-adrenergic inhibition of mitochondrial activity and angiogenesis arrest tumor growth
Nuevo-Tapioles, C., Santacatterina, F., Stamatakis, K., Nunez de Arenas, C., Gomez de Cedron, M., Formentini, L. and Cuezva, J. M.
Nat Commun. 2020 Jul 17, 11(1):3606.

Fumarate hydratase-deficient renal cell carcinoma cells respond to asparagine by activation of the unfolded protein response and stimulation of the hexosamine biosynthetic pathway
Panarsky, R., Crooks, D. R., Lane, A. N., Yang, Y., Cassel, T. A., Fan, T. W., Linehan, W. M. and Moscow, J. A.
Cancer Metab. 2020 Aug3, 8:7.

Ciclopirox activates PERK-dependent endoplasmic reticulum stress to drive cell death in colorectal cancer
Qi, J., Zhou, N., Li, L., Mo, S., Zhou, Y., Deng, Y., Chen, T., Shan, C., Chen, Q. and Lu, B.
Cell Death Dis. 2020 Jul 27, 11(7):582.

Niclosamide: drug repurposing for human chondrosarcoma treatment via the caspase-dependent mitochondrial apoptotic pathway
Yu, Q. S., Xin, H. R., Qiu, R. L., Deng, Z. L., Deng, F. and Yan, Z. J.
Am J Transl Res. 2020 Jul 15, 12(7):3688-3701.

CDK7 inhibitor THZ1 enhances antiPD-1 therapy efficacy via the p38alpha/MYC/PD-L1 signaling in non-small cell lung cancer
Wang, J., Zhang, R., Lin, Z., Zhang, S., Chen, Y., Tang, J., Hong, J., Zhou, X., Zong, Y., Xu, Y., Meng, R., Xu, S., Liu, L., Zhang, T., Yang, K., Dong, X. and Wu, G.
J Hematol Oncol. 2020 Jul 20, 13(1):99.

Endoplasmic Reticulum stress-dependent expression of ERO1L promotes aerobic glycolysis in Pancreatic Cancer
Zhang, J., Yang, J., Lin, C., Liu, W., Huo, Y., Yang, M., Jiang, S. H., Sun, Y. and Hua, R.
Theranostics. 2020 Jul 9, 10(18):8400-8414.

Inhibition of pyruvate dehydrogenase kinase1 by dicoumarol enhances the sensitivity of hepatocellular carcinoma cells to oxaliplatin via metabolic reprogramming
Xu, H., He, Y., Ma, J., Zhao, Y., Liu, Y., Sun, L. and Su, J.
Int J Oncol. 2020 Sep, 57(3):733-742.

Secretion of human soluble programmed cell death protein 1 by chimeric antigen receptor-modified T cells enhances anti-tumor efficacy
Zhang, A., Sun, Y., Wang, S., Du, J., Gao, X., Yuan, Y., Zhao, L., Yang, Y., Xu, L., Lei, Y., Duan, L., Xu, C., Ma, L., Wang, J., Hu, G., Chen, H., Wang, Q., Hu, L. and Zhang, B.
Cytotherapy. 2020 Dec, 22(12):734-743.

Long noncoding RNA NEAT1 modifies cell proliferation, colony formation, apoptosis, migration and invasion via the miR4500/BZW1 axis in ovarian cancer
Xu, H., Sun, X., Huang, Y., Si, Q. and Li, M.
Mol Med Rep. 2020 Oct, 22(4):3347-3357.

Low expression of ANT1 confers oncogenic properties to rhabdomyosarcoma tumor cells by modulating metabolism and death pathways
Vial, J., Huchede, P., Fagault, S., Basset, F., Rossi, M., Geoffray, J., Soldati, H., Bisaccia, J., Elsensohn, M. H., Creveaux, M., Neves, D., Blay, J. Y., Fauvelle, F., Bouquet, F., Streichenberger, N., Corradini, N., Bergeron, C., Maucort-Boulch, D., Castets, P., Carre, M., Weber, K. and Castets, M.
Cell Death Discov. 2020 Jul 24, 6:64.

HIF-1alpha regulates cellular metabolism, and Imatinib resistance by targeting phosphogluconate dehydrogenase in gastrointestinal stromal tumors
Xu, K., He, Z., Chen, M., Wang, N., Zhang, D., Yang, L., Xu, Z. and Xu, H.
Cell Death Dis. 2020 Jul 27, 11(7):586.

Oxidized ATM promotes breast cancer stem cell enrichment through energy metabolism reprogram-mediated acetyl-CoA accumulation
Yang, D., Peng, M., Hou, Y., Qin, Y., Wan, X., Zhu, P., Liu, S., Yang, L., Zeng, H., Jin, T., Qiu, Y., Li, Q. and Liu, M.
Cell Death Dis. 2020 Jul 3, 11(7):508.

Mito-oncology agent: fermented extract suppresses the Warburg effect, restores oxidative mitochondrial activity, and inhibits in vivo tumor growth
Bencze, G., Bencze, S., Rivera, K. D., Watson, J. D., Orfi, L., Tonks, N. K. and Pappin, D. J.
Sci Rep. 2020 Aug 25, 10(1):14174.

Defining the ATPome reveals cross-optimization of metabolic pathways
Bennett, N. K., Nguyen, M. K., Darch, M. A., Nakaoka, H. J., Cousineau, D., Ten Hoeve, J., Graeber, T. G., Schuelke, M., Maltepe, E., Kampmann, M., Mendelsohn, B. A., Nakamura, J. L. and Nakamura, K.
Nat Commun. 2020 Aug 28, 11(1):4319.

Autophagy regulates fatty acid availability for oxidative phosphorylation through mitochondria-endoplasmic reticulum contact sites
Bosc, C., Broin, N., Fanjul, M., Saland, E., Farge, T., Courdy, C., Batut, A., Masoud, R., Larrue, C., Skuli, S., Espagnolle, N., Pages, J. C., Carrier, A., Bost, F., Bertrand-Michel, J., Tamburini, J., Recher, C., Bertoli, S., Mansat-De Mas, V., Manenti, S., Sarry, J. E. and Joffre, C.
Nat Commun. 2020 Aug 13, 11(1):4056.

CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation
Beckermann, K. E., Hongo, R., Ye, X., Young, K., Carbonell, K., Healey, D. C. C., Siska, P. J., Barone, S., Roe, C. E., Smith, C. C., Vincent, B. G., Mason, F. M., Irish, J. M., Rathmell, W. K. and Rathmell, J. C.
JCI Insight. 2020 Aug 20, 5(16):e138729.

Combined Targeting of Estrogen Receptor Alpha and Exportin 1 in Metastatic Breast Cancers
Cotul, E. K., Zuo, Q., Santaliz-Casiano, A., Imir, O. B., Mogol, A. N., Tunc, E., Duong, K., Lee, J. K., Ramesh, R., Odukoya, E., Kesavadas, M. P., Ziogaite, M., Smith, B. P., Mao, C., Shapiro, D. J., Park, B. H., Katzenellenbogen, B. S., Daly, D., Aranda, E., O'Neill, J. D., Walker, C., Landesman, Y. and Madak-Erdogan, Z.
Cancers (Basel). 2020 Aug 24, 12(9):2397.

Monoamine Oxidase A is a Major Mediator of Mitochondrial Homeostasis and Glycolysis in Gastric Cancer Progression
Chen, L., Guo, L., Sun, Z., Yang, G., Guo, J., Chen, K., Xiao, R., Yang, X. and Sheng, L.
Cancer Manag Res. 2020 Sep 4, 12:8023-8035.

An Experimentally Defined Hypoxia Gene Signature in Glioblastoma and Its Modulation by Metformin
Calvo Tardon, M., Marinari, E., Migliorini, D., Bes, V., Tankov, S., Charrier, E., McKee, T. A., Dutoit, V., Dietrich, P. Y., Cosset, E. and Walker, P. R.
Biology (Basel). 2020 Sep 2, 9(9):264.

Cardiovascular Research

Cell identity and nucleo-mitochondrial genetic context modulate OXPHOS performance and determine somatic heteroplasmy dynamics
Lechuga-Vieco, A. V., Latorre-Pellicer, A., Johnston, I. G., Prota, G., Gileadi, U., Justo-Mendez, R., Acin-Perez, R., Martinez-de-Mena, R., Fernandez-Toro, J. M., Jimenez-Blasco, D., Mora, A., Nicolas-Avila, J. A., Santiago, D. J., Priori, S. G., Bolanos, J. P., Sabio, G., Criado, L. M., Ruiz-Cabello, J., Cerundolo, V., Jones, N. S. and Enriquez, J. A.
Sci Adv. 2020 Jul, 6(31):eaba5345.

Short high-fat diet interferes with the physiological maturation of the late adolescent mouse heart
Hynynen, H., Mutikainen, M., Naumenko, N., Shakirzyanova, A., Tuomainen, T. and Tavi, P.
Physiol Rep. 2020 Jul, 8(13):e14474.

Cancer‐induced cardiac atrophy adversely affects myocardial redox state and mitochondrial oxidative characteristics
Lee, D. E., Brown, J. L., Rosa‐Caldwell, M. E., Perry, R. A., Brown, L. A., Haynie, W. S., Washington, T. A., Wiggs, M. P., Rajaram, N. and Greene, N. P.
JCSM Rapid Communications. 2020 Aug 7, [epub ahead of print]

Mitochondrial DNA: Hotspot for Potential Gene Modifiers Regulating Hypertrophic Cardiomyopathy
Kargaran, P. K., Evans, J. M., Bodbin, S. E., Smith, J. G. W., Nelson, T. J., Denning, C. and Mosqueira, D.
J Clin Med. 2020 Jul 23, 9(8): 2349.

P-cresyl sulfate causes mitochondrial hyperfusion in H9C2 cardiomyoblasts
Huang, T. H., Yip, H. K., Sun, C. K., Chen, Y. L., Yang, C. C. and Lee, F. Y.
J Cell Mol Med. 2020 Aug, 24(15):8379-8390.

Mcl-1-mediated mitochondrial fission protects against stress but impairs cardiac adaptation to exercise
Moyzis, A. G., Lally, N. S., Liang, W., Leon, L. J., Najor, R. H., Orogo, A. M. and Gustafsson, A. B.
J Mol Cell Cardiol. 2020 Sep, 146:109-120.

Zishen Huoxue Recipe Protecting Mitochondrial Function of Hypoxic/Reoxygenated Myocardial Cells through mTORC1 Signaling Pathway
Liu, R., Chang, X., Li, J. and Shunyu, Y.
Evid Based Complement Alternat Med. 2020 Jul 27,  2020:8327307.

Sustained Activation of AMPK Enhances Differentiation of Human iPSC-Derived Cardiomyocytes via Sirtuin Activation
Sarikhani, M., Garbern, J. C., Ma, S., Sereda, R., Conde, J., Krahenbuhl, G., Escalante, G. O., Ahmed, A., Buenrostro, J. D. and Lee, R. T.
Stem Cell Reports. 2020 Aug 11, 15(2):498-514.

Nicotinamide nucleotide transhydrogenase (NNT) regulates mitochondrial ROS and endothelial dysfunction in response to angiotensin II
Rao, K. N. S., Shen, X., Pardue, S. and Krzywanski, D. M.
Redox Biol. 2020 Sep, 36:101650.

The Prophylactic Effect of Pinocembrin Against Doxorubicin-Induced Cardiotoxicity in an In Vitro H9c2 Cell Model
Sangweni, N. F., Moremane, M., Riedel, S., van Vuuren, D., Huisamen, B., Mabasa, L., Barry, R. and Johnson, R.
Front Pharmacol. 2020 Aug 5, 11:1172.

Lung-derived HMGB1 is detrimental for vascular remodeling of metabolically imbalanced arterial macrophages
Boytard, L., Hadi, T., Silvestro, M., Qu, H., Kumpfbeck, A., Sleiman, R., Fils, K. H., Alebrahim, D., Boccalatte, F., Kugler, M., Corsica, A., Gelb, B. E., Jacobowitz, G., Miller, G., Bellini, C., Oakes, J., Silvestre, J. S., Zangi, L. and Ramkhelawon, B.
Nat Commun. 2020 Aug 27, 11(1):4311.

Lactate Dehydrogenase A Governs Cardiac Hypertrophic Growth in Response to Hemodynamic Stress
Dai, C., Li, Q., May, H. I., Li, C., Zhang, G., Sharma, G., Sherry, A. D., Malloy, C. R., Khemtong, C., Zhang, Y., Deng, Y., Gillette, T. G., Xu, J., Scadden, D. T. and Wang, Z. V.
Cell Rep. 2020 Sep 1, 32(9):108087.

Cell Physiology Research

Cell identity and nucleo-mitochondrial genetic context modulate OXPHOS performance and determine somatic heteroplasmy dynamics
Lechuga-Vieco, A. V., Latorre-Pellicer, A., Johnston, I. G., Prota, G., Gileadi, U., Justo-Mendez, R., Acin-Perez, R., Martinez-de-Mena, R., Fernandez-Toro, J. M., Jimenez-Blasco, D., Mora, A., Nicolas-Avila, J. A., Santiago, D. J., Priori, S. G., Bolanos, J. P., Sabio, G., Criado, L. M., Ruiz-Cabello, J., Cerundolo, V., Jones, N. S. and Enriquez, J. A.
Sci Adv. 2020 Jul, 6(31):eaba5345.

Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors
Kim, H. N., Ponte, F., Nookaew, I., Ucer Ozgurel, S., Marques-Carvalho, A., Iyer, S., Warren, A., Aykin-Burns, N., Krager, K., Sardao, V. A., Han, L., de Cabo, R., Zhao, H., Jilka, R. L., Manolagas, S. C. and Almeida, M.
Sci Rep. 2020 Jul 20, 10(1):11933.

An extract of Lycium barbarum mimics exercise to improve muscle endurance through increasing type IIa oxidative muscle fibers by activating ERRgamma
Meng, J., Lv, Z., Sun, C., Qiao, X. and Chen, C.
FASEB J. 2020 Sep, 34(9):11460-11473.

GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes
Nicholas, D. A., Knight, V. S., Tonsfeldt, K. J., Terasaka, T., Molinar-Inglis, O., Stephens, S. B. Z., Trejo, J., Kauffman, A. S., Mellon, P. L. and Lawson, M. A.
Sci Rep. 2020 Aug 3, 10(1):13063.

Mcl-1-mediated mitochondrial fission protects against stress but impairs cardiac adaptation to exercise
Moyzis, A. G., Lally, N. S., Liang, W., Leon, L. J., Najor, R. H., Orogo, A. M. and Gustafsson, A. B.
J Mol Cell Cardiol. 2020 Sep, 146:109-120.

The Effect of Resveratrol on Mitochondrial Function in Myoblasts of Patients with the Common m.3243A>G Mutation
Motlagh Scholle, L., Schieffers, H., Al-Robaiy, S., Thaele, A., Dehghani, F., Lehmann Urban, D. and Zierz, S.
Biomolecules. 2020 Jul 24, 10(8):1103.

Testosterone Decreases Placental Mitochondrial Content and Cellular Bioenergetics
Mishra, J. S., Blesson, C. S. and Kumar, S.
Biology (Basel). 2020 Jul 20, 9(7):176.

Loss of Function of the Gene Encoding the Histone Methyltransferase KMT2D Leads to Deregulation of Mitochondrial Respiration
Pacelli, C., Adipietro, I., Malerba, N., Squeo, G. M., Piccoli, C., Amoresano, A., Pinto, G., Pucci, P., Lee, J. E., Ge, K., Capitanio, N. and Merla, G.
Cells. 2020 Jul 13, 9(7):1685.

Endogenous Carbon Monoxide Signaling Modulates Mitochondrial Function and Intracellular Glucose Utilization: Impact of the Heme Oxygenase Substrate Hemin
Stucki, D., Steinhausen, J., Westhoff, P., Krahl, H., Brilhaus, D., Massenberg, A., Weber, A. P. M., Reichert, A. S., Brenneisen, P. and Stahl, W.
Antioxidants (Basel). 2020 Jul 23, 9(8):652.

Berberine attenuates the abnormal ectopic lipid deposition in skeletal muscle
Yao, S., Yuan, Y., Zhang, H., Meng, X., Jin, L., Yang, J., Wang, W., Ning, G., Zhang, Y. and Zhang, Z.
Free Radic Biol Med. 2020 Nov 1, 159:66-75.

Erythromycin has therapeutic efficacy on muscle fatigue acting specifically on orosomucoid to increase muscle bioenergetics and physiological parameters of endurance
Wan, J., Qin, Z., Lei, H., Wang, P., Zhang, Y., Feng, J., Wei, J., Sun, Y. and Liu, X.
Pharmacol Res. 2020 Nov, 161:105118.

Regulation of glycolysis and the Warburg effect in wound healing
Vinaik, R., Barayan, D., Auger, C., Abdullahi, A. and Jeschke, M. G.
JCI Insight. 2020 Sep 3, 5(17):e138949.

Stable retention of chloramphenicol-resistant mtDNA to rescue metabolically impaired cells
Dawson, E. R., Patananan, A. N., Sercel, A. J. and Teitell, M. A.
Sci Rep. 2020 Aug 31, 10(1):14328.

Beta-aminoisobutyric acid is released by contracting human skeletal muscle and lowers insulin release from INS-1 832/3 cells by mediating mitochondrial energy metabolism
Barlow, J. P., Karstoft, K., Vigelso, A., Gram, M., Helge, J. W., Dela, F., Pappan, K., O'Neil, D., Dunn, W. and Solomon, T. P. J.
Metabol Open. 2020 Aug 27, 7:100053.

MIC26 and MIC27 cooperate to regulate cardiolipin levels and the landscape of OXPHOS complexes
Anand, R., Kondadi, A. K., Meisterknecht, J., Golombek, M., Nortmann, O., Riedel, J., Peifer-Weiss, L., Brocke-Ahmadinejad, N., Schlutermann, D., Stork, B., Eichmann, T. O., Wittig, I. and Reichert, A. S.
Life Sci Alliance. 2020 Aug 11, 3(10):e202000711.

A bioenergetic shift is required for spermatogonial differentiation
Chen, W., Zhang, Z., Chang, C., Yang, Z., Wang, P., Fu, H., Wei, X., Chen, E., Tan, S., Huang, W., Sun, L., Ni, T., Yang, Y. and Wang, Y.
Cell Discov. 2020 Aug 18, 6:56.

Osteocyte necrosis triggers osteoclast-mediated bone loss through macrophage-inducible C-type lectin
Andreev, D., Liu, M., Weidner, D., Kachler, K., Faas, M., Gruneboom, A., Schlotzer-Schrehardt, U., Munoz, L. E., Steffen, U., Grotsch, B., Killy, B., Kronke, G., Luebke, A. M., Niemeier, A., Wehrhan, F., Lang, R., Schett, G. and Bozec, A.
J Clin Invest. 2020 Sep 1, 130(9):4811-4830.

The Unique Cysteine of F-ATP Synthase OSCP Subunit Participates in Modulation of the Permeability Transition Pore
Carraro, M., Jones, K., Sartori, G., Schiavone, M., Antonucci, S., Kucharczyk, R., di Rago, J. P., Franchin, C., Arrigoni, G., Forte, M. and Bernardi, P.
Cell Rep. 2020 Sep 1, 32(9):108095.

Drug Discovery

Ascorbate sensitizes human osteosarcoma cells to the cytostatic effects of cisplatin
Oka, N., Komuro, A., Amano, H., Dash, S., Honda, M., Ota, K., Nishimura, S., Ueda, T., Akagi, M. and Okada, H.
Pharmacology Research & Perspectives. 2020 Aug, 8(4): e00632.

The Prophylactic Effect of Pinocembrin Against Doxorubicin-Induced Cardiotoxicity in an In Vitro H9c2 Cell Model
Sangweni, N. F., Moremane, M., Riedel, S., van Vuuren, D., Huisamen, B., Mabasa, L., Barry, R. and Johnson, R.
Front Pharmacol. 2020 Aug 5, 11:1172.

Coordinate beta-adrenergic inhibition of mitochondrial activity and angiogenesis arrest tumor growth
Nuevo-Tapioles, C., Santacatterina, F., Stamatakis, K., Nunez de Arenas, C., Gomez de Cedron, M., Formentini, L. and Cuezva, J. M.
Nat Commun. 2020 Jul 17, 11(1):3606.

Niclosamide: drug repurposing for human chondrosarcoma treatment via the caspase-dependent mitochondrial apoptotic pathway
Yu, Q. S., Xin, H. R., Qiu, R. L., Deng, Z. L., Deng, F. and Yan, Z. J.
Am J Transl Res. 2020 Jul 15, 12(7):3688-3701.

Novel Pt(IV) Prodrugs Displaying Antimitochondrial Effects
Tabrizi, L., Thompson, K., Mnich, K., Chintha, C., Gorman, A. M., Morrison, L., Luessing, J., Lowndes, N. F., Dockery, P., Samali, A. and Erxleben, A.
Mol Pharm. 2020 Aug 3, 17(8):3009-3023.

Food & Nutritional Research

Short high-fat diet interferes with the physiological maturation of the late adolescent mouse heart
Hynynen, H., Mutikainen, M., Naumenko, N., Shakirzyanova, A., Tuomainen, T. and Tavi, P.
Physiol Rep. 2020 Jul, 8(13):e14474.

An extract of Lycium barbarum mimics exercise to improve muscle endurance through increasing type IIa oxidative muscle fibers by activating ERRgamma
Meng, J., Lv, Z., Sun, C., Qiao, X. and Chen, C.
FASEB J. 2020 Sep, 34(9):11460-11473.

GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes
Nicholas, D. A., Knight, V. S., Tonsfeldt, K. J., Terasaka, T., Molinar-Inglis, O., Stephens, S. B. Z., Trejo, J., Kauffman, A. S., Mellon, P. L. and Lawson, M. A.
Sci Rep. 2020 Aug 3, 10(1):13063.

Fructose-palmitate based high calorie induce steatosis in HepG2 cells via mitochondrial dysfunction: An in vitro approach
Swapna Sasi, U. S., Sindhu, G. and Raghu, K. G.
Toxicol In Vitro. 2020 Oct, 68:104952.

A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters
Wang, Y., Zhu, Y., Niu, J., Deng, Q., Guo, S., Jiang, H., Peng, Z., Xue, Y., Peng, H., Xuan, L. and Pan, G.
Toxicol Appl Pharmacol. 2020 Oct 1, 404:115169.

Hepatobiology Research

A novel homozygous variant in MICOS13/QIL1 causes hepato-encephalopathy with mitochondrial DNA depletion syndrome
Kishita, Y., Shimura, M., Kohda, M., Akita, M., Imai-Okazaki, A., Yatsuka, Y., Nakajima, Y., Ito, T., Ohtake, A., Murayama, K. and Okazaki, Y.
Mol Genet Genomic Med. 2020 Oct, 8(10):e1427.

Fructose-palmitate based high calorie induce steatosis in HepG2 cells via mitochondrial dysfunction: An in vitro approach
Swapna Sasi, U. S., Sindhu, G. and Raghu, K. G.
Toxicol In Vitro. 2020 Oct, 68:104952.

Fatty acid mimetic PBI-4547 restores metabolic homeostasis via GPR84 in mice with non-alcoholic fatty liver disease
Simard, J. C., Thibodeau, J. F., Leduc, M., Tremblay, M., Laverdure, A., Sarra-Bournet, F., Gagnon, W., Ouboudinar, J., Gervais, L., Felton, A., Letourneau, S., Geerts, L., Cloutier, M. P., Hince, K., Corpuz, R., Blais, A., Quintela, V. M., Duceppe, J. S., Abbott, S. D., Blais, A., Zacharie, B., Laurin, P., Laplante, S. R., Kennedy, C. R. J., Hebert, R. L., Leblond, F. A., Grouix, B. and Gagnon, L.
Sci Rep. 2020 Jul 29, 10(1):12778.

A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters
Wang, Y., Zhu, Y., Niu, J., Deng, Q., Guo, S., Jiang, H., Peng, Z., Xue, Y., Peng, H., Xuan, L. and Pan, G.
Toxicol Appl Pharmacol. 2020 Oct 1, 404:115169.

Annexin A5 regulates hepatic macrophage polarization via directly targeting PKM2 and ameliorates NASH
Xu, F., Guo, M., Huang, W., Feng, L., Zhu, J., Luo, K., Gao, J., Zheng, B., Kong, L. D., Pang, T., Wu, X. and Xu, Q.
Redox Biol. 2020 Sep, 36:101634.

Inhibition of pyruvate dehydrogenase kinase1 by dicoumarol enhances the sensitivity of hepatocellular carcinoma cells to oxaliplatin via metabolic reprogramming
Xu, H., He, Y., Ma, J., Zhao, Y., Liu, Y., Sun, L. and Su, J.
Int J Oncol. 2020 Sep, 57(3):733-742.

Immunology Research

Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors
Kim, H. N., Ponte, F., Nookaew, I., Ucer Ozgurel, S., Marques-Carvalho, A., Iyer, S., Warren, A., Aykin-Burns, N., Krager, K., Sardao, V. A., Han, L., de Cabo, R., Zhao, H., Jilka, R. L., Manolagas, S. C. and Almeida, M.
Sci Rep. 2020 Jul 20, 10(1):11933.

Frontline Science: AMPK regulates metabolic reprogramming necessary for interferon production in human plasmacytoid dendritic cells
Hurley, H. J., Dewald, H., Rothkopf, Z. S., Singh, S., Jenkins, F., Deb, P., De, S., Barnes, B. J. and Fitzgerald-Bocarsly, P.
J Leukoc Biol. 2020 Jul 8, [epub ahead of print]

Anti-inflammatory Roles of Glucocorticoids Are Mediated by Foxp3(+) Regulatory T Cells via a miR-342-Dependent Mechanism
Kim, D., Nguyen, Q. T., Lee, J., Lee, S. H., Janocha, A., Kim, S., Le, H. T., Dvorina, N., Weiss, K., Cameron, M. J., Asosingh, K., Erzurum, S. C., Baldwin, W. M., 3rd, Lee, J. S. and Min, B.
Immunity. 2020 Sep 15, 53(3):581-596 e5.

Autoimmunity gene IRGM suppresses cGAS-STING and RIG-I-MAVS signaling to control interferon response
Jena, K. K., Mehto, S., Nath, P., Chauhan, N. R., Sahu, R., Dhar, K., Das, S. K., Kolapalli, S. P., Murmu, K. C., Jain, A., Krishna, S., Sahoo, B. S., Chattopadhyay, S., Rusten, T. E., Prasad, P., Chauhan, S. and Chauhan, S.
EMBO Rep. 2020 Sep 3, 21(9):e50051.

Apoptotic cell therapy for cytokine storm associated with acute severe sepsis
Karbian, N., Abutbul, A., El-Amore, R., Eliaz, R., Beeri, R., Reicher, B. and Mevorach, D.
Cell Death Dis. 2020 Jul 15, 11(7):535.

Denervation-induced loss of skeletal muscle mass influences immune homeostasis and accelerates the disease progression of lupus nephritis
Liu, S., Kiyoi, T., Takemasa, E. and Mogi, M.
JCSM Clinical Reports. 2020 Jul 26, 5(4):108-120.

The c-Rel-c-Myc axis controls metabolism and proliferation of human T leukemia cells
Li, X., Luo, G., Li, T., Sun, H., Wang, W., Eiler, E., Goldsmith, J. R. and Chen, Y. H.
Mol Immunol. 2020 Sep, 125:115-122.

Tonic TCR Signaling Inversely Regulates the Basal Metabolism of CD4(+) T Cells
Milam, A. A. V., Bartleson, J. M., Buck, M. D., Chang, C. H., Sergushichev, A., Donermeyer, D. L., Lam, W. Y., Pearce, E. L., Artyomov, M. N. and Allen, P. M.
Immunohorizons. 2020 Aug 7, 4(8):485-497.

MTFMT deficiency correlates with reduced mitochondrial integrity and enhanced host susceptibility to intracellular infection
Seo, J. H., Hwang, C. S. and Yoo, J. Y.
Sci Rep. 2020 Jul 7, 10(1):11183.

Platelet factor 4 enhances CD4(+) T effector memory cell responses via Akt-PGC1alpha-TFAM signaling-mediated mitochondrial biogenesis
Tan, S., Li, S., Min, Y., Gistera, A., Moruzzi, N., Zhang, J., Sun, Y., Andersson, J., Malmstrom, R. E., Wang, M., Berggren, P. O., Schlisio, S., Liao, W., Ketelhuth, D. F. J., Ma, C. and Li, N.
J Thromb Haemost. 2020 Oct, 18(10):2685-2700.

Identification of Lysinibacillus sphaericus Binary toxin binding proteins in a malarial mosquito cell line by proteomics: A novel approach towards improving mosquito control
Riaz, M. A., Adang, M. J., Hua, G., Rezende, T. M. T., Rezende, A. M. and Shen, G. M.
J Proteomics. 2020 Sep 15, 227:103918.

Classically activated mouse macrophages produce methylglyoxal that induces a TLR4- and RAGE-independent proinflammatory response
Prantner, D., Nallar, S., Richard, K., Spiegel, D., Collins, K. D. and Vogel, S. N.
J Leukoc Biol. 2020 Jul 17, [epub ahead of print]

Annexin A5 regulates hepatic macrophage polarization via directly targeting PKM2 and ameliorates NASH
Xu, F., Guo, M., Huang, W., Feng, L., Zhu, J., Luo, K., Gao, J., Zheng, B., Kong, L. D., Pang, T., Wu, X. and Xu, Q.
Redox Biol. 2020 Sep, 36:101634.

T cell-specific deletion of Pgam1 reveals a critical role for glycolysis in T cell responses
Toriyama, K., Kuwahara, M., Kondoh, H., Mikawa, T., Takemori, N., Konishi, A., Yorozuya, T., Yamada, T., Soga, T., Shiraishi, A. and Yamashita, M.
Commun Biol. 2020 Jul 24, 3(1):394.

Lung-derived HMGB1 is detrimental for vascular remodeling of metabolically imbalanced arterial macrophages
Boytard, L., Hadi, T., Silvestro, M., Qu, H., Kumpfbeck, A., Sleiman, R., Fils, K. H., Alebrahim, D., Boccalatte, F., Kugler, M., Corsica, A., Gelb, B. E., Jacobowitz, G., Miller, G., Bellini, C., Oakes, J., Silvestre, J. S., Zangi, L. and Ramkhelawon, B.
Nat Commun. 2020 Aug 27, 11(1):4311.

Osteocyte necrosis triggers osteoclast-mediated bone loss through macrophage-inducible C-type lectin
Andreev, D., Liu, M., Weidner, D., Kachler, K., Faas, M., Gruneboom, A., Schlotzer-Schrehardt, U., Munoz, L. E., Steffen, U., Grotsch, B., Killy, B., Kronke, G., Luebke, A. M., Niemeier, A., Wehrhan, F., Lang, R., Schett, G. and Bozec, A.
J Clin Invest. 2020 Sep 1, 130(9):4811-4830.

NADPH oxidase and mitochondria are relevant sources of superoxide anion in the oxinflammatory response of macrophages exposed to airborne particulate matter
Caceres, L., Paz, M. L., Garces, M., Calabro, V., Magnani, N. D., Martinefski, M., Martino Adami, P. V., Caltana, L., Tasat, D., Morelli, L., Tripodi, V., Valacchi, G., Alvarez, S., Gonzalez Maglio, D., Marchini, T. and Evelson, P.
Ecotoxicol Environ Saf. 2020 Dec 1, 205:111186.

Infectious Disease Research

Identification of Lysinibacillus sphaericus Binary toxin binding proteins in a malarial mosquito cell line by proteomics: A novel approach towards improving mosquito control
Riaz, M. A., Adang, M. J., Hua, G., Rezende, T. M. T., Rezende, A. M. and Shen, G. M.
J Proteomics. 2020 Sep 15, 227:103918.

Novel Pt(IV) Prodrugs Displaying Antimitochondrial Effects
Tabrizi, L., Thompson, K., Mnich, K., Chintha, C., Gorman, A. M., Morrison, L., Luessing, J., Lowndes, N. F., Dockery, P., Samali, A. and Erxleben, A.
Mol Pharm. 2020 Aug 3, 17(8):3009-3023.

Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1alpha/Glycolysis-Dependent Axis
Codo, A. C., Davanzo, G. G., Monteiro, L. B., de Souza, G. F., Muraro, S. P., Virgilio-da-Silva, J. V., Prodonoff, J. S., Carregari, V. C., de Biagi Junior, C. A. O., Crunfli, F., Jimenez Restrepo, J. L., Vendramini, P. H., Reis-de-Oliveira, G., Bispo Dos Santos, K., Toledo-Teixeira, D. A., Parise, P. L., Martini, M. C., Marques, R. E., Carmo, H. R., Borin, A., Coimbra, L. D., Boldrini, V. O., Brunetti, N. S., Vieira, A. S., Mansour, E., Ulaf, R. G., Bernardes, A. F., Nunes, T. A., Ribeiro, L. C., Palma, A. C., Agrela, M. V., Moretti, M. L., Sposito, A. C., Pereira, F. B., Velloso, L. A., Vinolo, M. A. R., Damasio, A., Proenca-Modena, J. L., Carvalho, R. F., Mori, M. A., Martins-de-Souza, D., Nakaya, H. I., Farias, A. S. and Moraes-Vieira, P. M.
Cell Metab. 2020 Sep 1, 32(3):437-446 e5.

Microbial Research

A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing
Mok, B. Y., de Moraes, M. H., Zeng, J., Bosch, D. E., Kotrys, A. V., Raguram, A., Hsu, F., Radey, M. C., Peterson, S. B., Mootha, V. K., Mougous, J. D. and Liu, D. R.
Nature. 2020 Jul, 583(7817):631-637.

Tonic TCR Signaling Inversely Regulates the Basal Metabolism of CD4(+) T Cells
Milam, A. A. V., Bartleson, J. M., Buck, M. D., Chang, C. H., Sergushichev, A., Donermeyer, D. L., Lam, W. Y., Pearce, E. L., Artyomov, M. N. and Allen, P. M.
Immunohorizons. 2020 Aug 7, 4(8):485-497.

 

 

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